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DENND1B anticorps (N-Term)

DENND1B Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB28056 unconjugated
N° du produit ABIN654339
  • Antigène Voir toutes DENND1B Anticorps
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Épitope
    • 15
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-68, N-Term
    Reactivité
    • 31
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 1
    Lapin
    Clonalité
    • 46
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DENND1B est non-conjugé
    Application
    • 39
    • 16
    • 15
    • 13
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This DENND1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B.
    Clone
    RB28056
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Autre désignation
    DENND1B (DENND1B Produits)
    Synonymes
    anticorps C1ORF18, anticorps C1orf218, anticorps FAM31B, anticorps 4632404N19Rik, anticorps 4930467M19Rik, anticorps 6820401H01Rik, anticorps F730008N07Rik, anticorps Fam31b, anticorps si:ch211-195i21.1, anticorps DENN domain containing 1B, anticorps DENN/MADD domain containing 1B, anticorps DENND1B, anticorps dennd1b, anticorps Dennd1b
    Sujet
    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).
    Poids moléculaire
    86552
    ID gène
    163486
    NCBI Accession
    NP_001182144, NP_001182145, NP_659414
    UniProt
    Q6P3S1
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