This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This INPP5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 950-979 amino acids from the C-terminal region of human INPP5B.
anticorps 75kDa, anticorps AW260155, anticorps INPP5P, anticorps 5PTase, anticorps inositol polyphosphate-5-phosphatase B, anticorps type II inositol 1,4,5-trisphosphate 5-phosphatase-like, anticorps inositol polyphosphate-5-phosphatase B L homeolog, anticorps inositol polyphosphate 5-phosphatase OCRL-1, anticorps INPP5B, anticorps LOC100224437, anticorps inpp5b.L, anticorps LOC100159919, anticorps Inpp5b
Sujet
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].