CES2 anticorps (AA 340-369)

N° du produit ABIN654618

Détail du produit anti-CES2 anticorps

Antigène: CES2 (Carboxylesterase 2 (CES2))

Épitope: AA 340-369

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CES2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CES2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-369 amino acids from the Central region of human CES2.

Clone: RB18998

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:25. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CES2 (ABIN654618)

Shang, Liu, Chen, Ning, Xiong, Liu, Mao, Hu, Yang: "Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells." dans: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-13, (2015) (PubMed).

Chen, Wang, Ning, Hu, Liu, Xiong, Wu, Liu, Hu, Yang: "Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1?/Stra13 pathway." dans: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-12, (2015) (PubMed).

Détails sur CES2

Antigène: CES2 (Carboxylesterase 2 (CES2))

Autre désignation: CES2 (CES2 Produits)

Synonymes: anticorps CE-2, anticorps CES2A1, anticorps PCE-2, anticorps iCE, anticorps Ces2, anticorps im:6908784, anticorps si:dkey-38l12.2, anticorps zgc:153863, anticorps ce-2, anticorps ces2a1, anticorps pce-2, anticorps carboxylesterase 2, anticorps liver carboxylesterase 2, anticorps cocaine esterase, anticorps carboxylesterase 2 (intestine, liver), anticorps CES2, anticorps Ces2, anticorps LOC100343300, anticorps LOC100734360, anticorps ces2

Sujet: CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.

Poids moléculaire: 61807

ID gène: 8824

NCBI Accession: NP_003860, NP_932327

UniProt: O00748