Complement C2 anticorps (N-Term)

N° du produit ABIN654619

Détail du produit anti-Complement C2 anticorps

Antigène: Complement C2

Épitope: AA 147-176, N-Term

Reactivité: Humain, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement C2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the N-terminal region of human C2.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 AA from the N-terminal region of human C2.

Clone: RB18356

Isotype: Ig Fraction

Information d'application

Indications d'application: WB = 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.26 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Complement C2

Antigène: Complement C2

Autre désignation: C2 (Complement C2 Produits)

Synonymes: anticorps CO2, anticorps complement C2, anticorps complement component 2 (within H-2S), anticorps C2

Sujet: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Synonyms: Complement C2,C2,

Poids moléculaire: 83268 DA

ID gène: 717

NCBI Accession: NP_000054

UniProt: P06681