Cyclin T1 anticorps (AA 253-281)
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- Antigène Voir toutes Cyclin T1 (CCNT1) Anticorps
- Cyclin T1 (CCNT1)
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Épitope
- AA 253-281
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Cyclin T1 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This CCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids from the Central region of human CCNT1.
- Clone
- RB19562
- Isotype
- Ig Fraction
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- Indications d'application
- WB: 1:1000. WB: 1:1000. WB: 1:1000. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- Cyclin T1 (CCNT1)
- Autre désignation
- CCNT1 (CCNT1 Produits)
- Sujet
- CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.
- Poids moléculaire
- 80685
- ID gène
- 904
- NCBI Accession
- NP_001231
- UniProt
- O60563
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