GM-CSF anticorps (AA 59-85)

N° du produit ABIN654647

Détail du produit anti-GM-CSF anticorps

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Épitope: AA 59-85

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GM-CSF est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CSF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-85 amino acids from the Central region of human CSF2.

Clone: RB23360

Isotype: IgG

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-GM-CSF (ABIN654647)

Stone, Vanderman, Willey, Long, Register, Shively, Stehle, Loeser, Ferguson: "Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion." dans: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, (2015) (PubMed).

Détails sur GM-CSF

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Autre désignation: CSF2 (CSF2 Produits)

Synonymes: anticorps GMCSF, anticorps GM-CSF, anticorps CSF2, anticorps Csfgm, anticorps Gm-CSf, anticorps MGI-IGM, anticorps Gm-csf, anticorps Gmcsf, anticorps CSF, anticorps colony stimulating factor 2, anticorps colony stimulating factor 2 (granulocyte-macrophage), anticorps CSF2, anticorps Csf2

Sujet: CSF2 is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq].

Poids moléculaire: 16295

ID gène: 1437

NCBI Accession: NP_000749

UniProt: P04141

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin