RENT2/UPF2 anticorps (AA 630-656)

N° du produit ABIN654649

Détail du produit anti-RENT2/UPF2 anticorps

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Épitope: AA 630-656

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RENT2/UPF2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UPF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 630-656 amino acids from the Central region of human UPF2.

Clone: RB21963

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur RENT2/UPF2

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Autre désignation: UPF2 (UPF2 Produits)

Synonymes: anticorps HUPF2, anticorps RENT2, anticorps smg-3, anticorps UPF2, regulator of nonsense mediated mRNA decay, anticorps UPF2 regulator of nonsense transcripts homolog (yeast), anticorps UPF2, anticorps Upf2, anticorps upf2

Sujet: UPF2 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p.

Poids moléculaire: 147810

ID gène: 26019

NCBI Accession: NP_056357, NP_542166

UniProt: Q9HAU5