IBTK anticorps (AA 586-613)
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- Antigène Voir toutes IBTK Anticorps
- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
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Épitope
- AA 586-613
- Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IBTK est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This IBTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-613 amino acids from the Central region of human IBTK.
- Clone
- RB24652
- Isotype
- Ig Fraction
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- Indications d'application
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
- Autre désignation
- IBTK (IBTK Produits)
- Synonymes
- anticorps IBTK, anticorps fi40c08, anticorps wu:fi40c08, anticorps DKFZp468J085, anticorps BTBD26, anticorps BTKI, anticorps RP1-93K22.1, anticorps 5430411K16Rik, anticorps AA409502, anticorps mKIAA1417, anticorps inhibitor of Bruton tyrosine kinase, anticorps inhibitor of Bruton agammaglobulinemia tyrosine kinase, anticorps inhibitor of Bruton tyrosine kinase L homeolog, anticorps IBTK, anticorps ibtk, anticorps Ibtk, anticorps ibtk.L
- Sujet
- The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
- Poids moléculaire
- 150528
- ID gène
- 25998
- NCBI Accession
- NP_056340
- UniProt
- Q9P2D0
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