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SPACA1 anticorps (N-Term)

SPACA1 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB25586 unconjugated
N° du produit ABIN654730
  • Antigène Voir toutes SPACA1 Anticorps
    SPACA1 (Sperm Acrosome Associated 1 (SPACA1))
    Épitope
    • 13
    • 7
    • 5
    • 1
    • 1
    AA 46-74, N-Term
    Reactivité
    • 22
    • 1
    • 1
    Humain
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp SPACA1 est non-conjugé
    Application
    • 16
    • 15
    • 15
    • 12
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This SACA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human SACA1.
    Clone
    RB25586
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    SPACA1 (Sperm Acrosome Associated 1 (SPACA1))
    Autre désignation
    SACA1 (SPACA1 Produits)
    Synonymes
    anticorps SAMP32, anticorps 1700124L11Rik, anticorps 4930540L03Rik, anticorps sperm acrosome associated 1, anticorps SPACA1, anticorps Spaca1
    Sujet
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
    Poids moléculaire
    32143
    ID gène
    81833
    NCBI Accession
    NP_112222
    UniProt
    Q9HBV2
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