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CASP5 anticorps (AA 162-191)

CASP5 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB18988 unconjugated
N° du produit ABIN654898
  • Antigène Voir toutes CASP5 Anticorps
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Épitope
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-191
    Reactivité
    • 43
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 3
    Lapin
    Clonalité
    • 33
    • 10
    Polyclonal
    Conjugué
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp CASP5 est non-conjugé
    Application
    • 25
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This CASP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human CASP5.
    Clone
    RB18988
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CASP5 Anticorps primaire
  • Indications d'application
    WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Autre désignation
    CASP5 (CASP5 Produits)
    Synonymes
    anticorps ICE(rel)III, anticorps ICEREL-III, anticorps ICH-3, anticorps CASP5, anticorps caspase 5, anticorps caspase-5, anticorps CASP5, anticorps LOC100437308
    Sujet
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
    Poids moléculaire
    49736
    ID gène
    838
    NCBI Accession
    NP_001129581, NP_001129582, NP_001129584, NP_004338
    UniProt
    P51878
    Pathways
    Inflammasome
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