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FZD6 anticorps (AA 493-520)

FZD6 Reactivité: Humain WB Hôte: Lapin Polyclonal RB25725 unconjugated
N° du produit ABIN654962
  • Antigène Voir toutes FZD6 Anticorps
    FZD6 (Frizzled Family Receptor 6 (FZD6))
    Épitope
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 493-520
    Reactivité
    • 36
    • 13
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 36
    • 2
    • 2
    • 1
    Lapin
    Clonalité
    • 39
    • 2
    Polyclonal
    Conjugué
    • 28
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FZD6 est non-conjugé
    Application
    • 25
    • 17
    • 7
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This FZD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 493-520 amino acids from the Central region of human FZD6.
    Clone
    RB25725
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FZD6 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    FZD6 (Frizzled Family Receptor 6 (FZD6))
    Autre désignation
    FZD6 (FZD6 Produits)
    Synonymes
    anticorps zgc:65879, anticorps zgc:77440, anticorps fz6, anticorps frz6, anticorps Xfrz6, anticorps frizzled6, anticorps frizzled-6, anticorps FZ-6, anticorps FZ6, anticorps HFZ6, anticorps NDNC10, anticorps Frizzled-6, anticorps Fz6, anticorps frizzled class receptor 6, anticorps frizzled class receptor 6 S homeolog, anticorps fzd6, anticorps fzd6.S, anticorps FZD6, anticorps Fzd6
    Sujet
    This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
    Poids moléculaire
    79292
    ID gène
    8323
    NCBI Accession
    NP_001158087, NP_001158088, NP_003497
    UniProt
    O60353
    Pathways
    Signalisation WNT, Tube Formation
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