COCH anticorps (C-Term)
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- Antigène Voir toutes COCH Anticorps
- COCH (Cochlin (COCH))
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Épitope
- AA 492-520, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp COCH est non-conjugé
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Application
- Western Blotting (WB)
- Homologie
- B
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This COCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the C-terminal region of human COCH.
- Clone
- RB20929
- Isotype
- Ig Fraction
- Top Product
- Discover our top product COCH Anticorps primaire
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- Indications d'application
- WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- COCH (Cochlin (COCH))
- Autre désignation
- COCH (COCH Produits)
- Synonymes
- anticorps AW122937, anticorps Coch-5B2, anticorps D12H14S564E, anticorps COCH-5B2, anticorps COCH5B2, anticorps DFNA9, anticorps cochlin, anticorps Coch, anticorps COCH
- Sujet
- The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq].
- Poids moléculaire
- 59483
- ID gène
- 1690
- NCBI Accession
- NP_001128530, NP_004077
- UniProt
- O43405
- Pathways
- Sensory Perception of Sound
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