MITF anticorps (N-Term)

N° du produit ABIN655506

Détail du produit anti-MITF anticorps

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Épitope: AA 1-28, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MITF est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MITF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human MITF.

Clone: RB18810

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. WB: 1:2000. IHC: 1:800. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MITF (ABIN655506)

Ishii, Ryu, Suzuki: "Lactoferrin inhibits melanogenesis by down-regulating MITF in melanoma cells and normal melanocytes." dans: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 95, Issue 1, pp. 119-125, (2017) (PubMed).

Détails sur MITF

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: MITF (MITF Produits)

Synonymes: anticorps MITF, anticorps ws2a, anticorps mitfa, anticorps MITF-A, anticorps LOC100313655, anticorps mitfb, anticorps CMM8, anticorps MI, anticorps WS2, anticorps WS2A, anticorps bHLHe32, anticorps BCC2, anticorps Bhlhe32, anticorps Gsfbcc2, anticorps Vitiligo, anticorps Wh, anticorps bw, anticorps mi, anticorps vit, anticorps MITF-H, anticorps MITF-M, anticorps CMI9, anticorps melanogenesis associated transcription factor, anticorps microphthalmia-associated transcription factor, anticorps microphthalmia-associated transcription factor S homeolog, anticorps Microphthalmia, anticorps MITF, anticorps mitf, anticorps LOC100313655, anticorps mitf.S, anticorps LOC100534525, anticorps MICROP, anticorps Mitf

Sujet: This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 58795

ID gène: 4286

NCBI Accession: NP_000239, NP_001171896, NP_006713, NP_937801, NP_937802, NP_937820, NP_937821

UniProt: O75030

Pathways: Chromatin Binding