IRF9 anticorps (AA 75-104)
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- Antigène Voir toutes IRF9 Anticorps
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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Épitope
- AA 75-104
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF9 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids of human IRF9.
- Clone
- RB19229
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IRF9 Anticorps primaire
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- Indications d'application
- IF: 1:10~50. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- Autre désignation
- IRF9 (IRF9 Produits)
- Sujet
- IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- Poids moléculaire
- 43696
- ID gène
- 10379
- NCBI Accession
- NP_006075
- UniProt
- Q00978
- Pathways
- Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C
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