CHRNA10 anticorps (AA 179-206)

N° du produit ABIN656120

Détail du produit anti-CHRNA10 anticorps

Antigène: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Épitope: AA 179-206

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10.

Clone: RB32240

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur CHRNA10

Antigène: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Autre désignation: CHRNA10 (CHRNA10 Produits)

Synonymes: anticorps si:dkey-24p1.3, anticorps ALPHA 10 nAChR, anticorps cholinergic receptor, nicotinic, alpha polypeptide 10, anticorps cholinergic receptor nicotinic alpha 10 subunit, anticorps cholinergic receptor, nicotinic, alpha 10a, anticorps neuronal acetylcholine receptor subunit alpha-10, anticorps cholinergic receptor, nicotinic, alpha 10 (neuronal), anticorps Chrna10, anticorps CHRNA10, anticorps chrna10a, anticorps LOC100344381

Sujet: CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Poids moléculaire: 49705

ID gène: 57053

NCBI Accession: NP_065135

UniProt: Q9GZZ6

Pathways: Sensory Perception of Sound, Synaptic Membrane