RHOB anticorps (AA 104-137)

N° du produit ABIN656198

Détail du produit anti-RHOB anticorps

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Épitope: AA 104-137

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ARHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-137 amino acids from the Central region of human ARHB.

Clone: RB14498

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:4000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: ARHB Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur RHOB

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Autre désignation: ARHB (RHOB Produits)

Synonymes: anticorps ARH6, anticorps ARHB, anticorps MST081, anticorps MSTP081, anticorps RHOH6, anticorps AA017882, anticorps Arh6, anticorps Arhb, anticorps RHO, anticorps arha, anticorps rhoa, anticorps wu:fj42e08, anticorps zgc:92206, anticorps rhob, anticorps xrhob, anticorps ras homolog family member B, anticorps ras homolog gene family, member Ab, anticorps ras homolog family member B S homeolog, anticorps RHOB, anticorps Rhob, anticorps rhoab, anticorps rhob.S

Sujet: ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.

Poids moléculaire: 22123

ID gène: 388

NCBI Accession: NP_004031

UniProt: P62745