Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
Homologie
B
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC.
anticorps SFTPC, anticorps SPC, anticorps SP-C, anticorps psp-c, anticorps sftp2, anticorps xSP-C, anticorps Bricd6, anticorps SP5, anticorps Sftp-2, anticorps Sftp2, anticorps pro-SpC, anticorps BRICD6, anticorps PSP-C, anticorps SFTP2, anticorps SMDP2, anticorps surfactant protein C, anticorps surfactant, pulmonary-associated protein C S homeolog, anticorps surfactant, pulmonary-associated protein C, anticorps surfactant associated protein C, anticorps SFTPC, anticorps sftpc.S, anticorps sftpc, anticorps Sftpc
Sujet
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.