Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SLC12A7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human SLC12A7.
anticorps SLC12A7, anticorps KCC4, anticorps Kcc4, anticorps Slc12a5, anticorps AA408796, anticorps D13Ertd261e, anticorps solute carrier family 12 (potassium/chloride transporters), member 7, anticorps solute carrier family 12 member 7, anticorps solute carrier family 12, member 7, anticorps SLC12A7, anticorps Slc12a7
Sujet
SLC12A7 mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity).