Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SLC16A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 433-462 amino acids from the C-terminal region of human SLC16A3.
anticorps MCT 3, anticorps MCT 4, anticorps MCT-3, anticorps MCT-4, anticorps MCT3, anticorps MCT4, anticorps mct, anticorps slc16a3b, anticorps Mct3, anticorps Mct4, anticorps MCT4b, anticorps wu:fd20b02, anticorps wu:fi38f12, anticorps zgc:55905, anticorps solute carrier family 16 member 3, anticorps solute carrier family 16 member 3 L homeolog, anticorps solute carrier family 16 (monocarboxylic acid transporters), member 3, anticorps solute carrier family 16 (monocarboxylate transporter), member 3, anticorps SLC16A3, anticorps slc16a3.L, anticorps Slc16a3, anticorps slc16a3
Sujet
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1, MIM 600682) and MCT2 (SLC16A7, MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).