This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This CHMP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP6.
anticorps chmp6, anticorps vps20, anticorps 2400004G01Rik, anticorps VPS20, anticorps RGD1565325, anticorps chmp6l, anticorps flj11749l, anticorps wu:fb79d02, anticorps zgc:110067, anticorps charged multivesicular body protein 6, anticorps charged multivesicular body protein 6 L homeolog, anticorps charged multivesicular body protein 6 S homeolog, anticorps charged multivesicular body protein 6b, anticorps LOC100280982, anticorps chmp6.L, anticorps chmp6.S, anticorps CHMP6, anticorps chmp6, anticorps Tsp_08316, anticorps Chmp6, anticorps chmp6b
Sujet
CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).