This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human GDF15.
Bone morphogenetic proteins (e.g., BMP9, MIM 605120) are members of the transforming growth factor-beta (see TGFB1, MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.