TMEM43 anticorps (AA 195-223)

N° du produit ABIN656549

Détail du produit anti-TMEM43 anticorps

Antigène: TMEM43 (Transmembrane Protein 43 (TMEM43))

Épitope: AA 195-223

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM43 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43.

Clone: RB32139

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: TMEM43 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur TMEM43

Antigène: TMEM43 (Transmembrane Protein 43 (TMEM43))

Autre désignation: TMEM43 (TMEM43 Produits)

Synonymes: anticorps zgc:85946, anticorps ARVC5, anticorps ARVD5, anticorps EDMD7, anticorps LUMA, anticorps 1200015A22Rik, anticorps transmembrane protein 43, anticorps TMEM43, anticorps tmem43, anticorps Tmem43

Sujet: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Poids moléculaire: 44876

ID gène: 79188

NCBI Accession: NP_077310

UniProt: Q9BTV4