This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This APBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the Central region of human APBA2.
anticorps MGC83599, anticorps D15S1518E, anticorps HsT16821, anticorps LIN-10, anticorps MGC:14091, anticorps MINT2, anticorps X11-BETA, anticorps X11L, anticorps X11-like, anticorps XllL, anticorps mXllL, anticorps Mint2, anticorps amyloid beta precursor protein binding family A member 2, anticorps amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog, anticorps amyloid beta (A4) precursor protein-binding, family A, member 2, anticorps APBA2, anticorps apba2.L, anticorps Apba2
Sujet
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].