SPHK1 anticorps
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- Antigène Voir toutes SPHK1 Anticorps
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SPHK1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human SPHK1
- Isotype
- IgG
- Top Product
- Discover our top product SPHK1 Anticorps primaire
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- Indications d'application
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
- Autre désignation
- SPHK1 (SPHK1 Produits)
- Synonymes
- anticorps CG1747, anticorps Dmel\\CG1747, anticorps SK1, anticorps Sphk1, anticorps SPHK1, anticorps F18E5.160, anticorps F18E5_160, anticorps sphingosine kinase 1, anticorps SPHK, anticorps 1110006G24Rik, anticorps Sk1, anticorps Spk1, anticorps Sphingosine kinase 1, anticorps sphingosine kinase 1, anticorps sphingosine kinase 1 L homeolog, anticorps Sk1, anticorps SPHK1, anticorps sphk1.L, anticorps Sphk1
- Sujet
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Synonyms: SK 1,SK1,Sphingosine kinase 1,SPHK 1,SPHK,Sphk1,SPHK1,SPK ,SPK 1
Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
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Observed_MW: 55kDa
Calculated_MW: 42kDa/43kDa/51kDa
- ID gène
- 8877
- UniProt
- Q9NYA1
- Pathways
- VEGF Signaling
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