NACA anticorps

N° du produit ABIN6566781

Détail du produit anti-NACA anticorps

Antigène: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NACA est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human NACA

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NACA

Antigène: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Autre désignation: NACA (NACa1 Produits)

Synonymes: anticorps AL022831, anticorps AL024382, anticorps Gm1878, anticorps mKIAA0363, anticorps skNAC, anticorps ik:tdsubc_2b5, anticorps nkn, anticorps tdsubc_2b5, anticorps xx:tdsubc_2b5, anticorps NACA1, anticorps nascent polypeptide-associated complex alpha polypeptide, anticorps nascent polypeptide-associated complex alpha subunit, anticorps Naca, anticorps naca, anticorps NACA

Sujet:

Synonyms: Alpha NAC,Alpha-NAC,Hom s 2.02,HSD48 ,MGC117224,NAC-alpha,naca,NACA/1.9.2,NACA,NACA1,Nascent polypeptide associated complex alpha polypeptide,Nascent polypeptide associated complex alpha subunit,Nascent polypeptide associated complex subunit alpha,Nascent polypeptide-associated complex subunit alpha

Background: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.

Poids moléculaire:

Observed_MW: 37kDa, 39kDa

Calculated_MW: 23kDa/94kDa/205kDa

ID gène: 4666

UniProt: Q13765

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development