RASGRP1 anticorps
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- Antigène Voir toutes RASGRP1 Anticorps
- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RASGRP1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human RASGRP1
- Isotype
- IgG
- Top Product
- Discover our top product RASGRP1 Anticorps primaire
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- Indications d'application
- WB 1:1000 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
- Autre désignation
- RASGRP1 (RASGRP1 Produits)
- Synonymes
- anticorps Rasgrp, anticorps CALDAG-GEFI, anticorps CALDAG-GEFII, anticorps RASGRP, anticorps V, anticorps hRasGRP1, anticorps RAS guanyl releasing protein 1, anticorps Rasgrp1, anticorps RASGRP1
- Sujet
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Synonyms: Calcium and DAG-regulated guanine nucleotide exchange factor II,CALDAG-GEFI,CalDAG-GEFII,GRP1,Guanine nucleotide exchange factor, calcium and DAG regulated, Rap1A,hRasGRP1,Ras activator RasGRP,RAS guanyl nucleotide releasing protein 1,RAS guanyl releasing protein 1 (calcium and DAG-regulated),RAS guanyl releasing protein 1,RAS guanyl-releasing protein 1,Ras guanyl-releasing protein,RASGRP,rasgrp1,V
Background: This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).
- Poids moléculaire
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Observed_MW: 90kDa
Calculated_MW: 55kDa/62kDa/68kDa/86kDa/90kDa
- ID gène
- 10125
- UniProt
- O95267
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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