Fibrillarin anticorps

N° du produit ABIN6567124

Détail du produit anti-Fibrillarin anticorps

Antigène: Fibrillarin (FBL)

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrillarin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Affinity purification

Immunogène: Recombinant protein of human FBL

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Fibrillarin

Antigène: Fibrillarin (FBL)

Autre désignation: FBL (FBL Produits)

Sujet:

Synonyms: 34 kD nucleolar scleroderma antigen,34 kDa nucleolar scleroderma antigen,Fbl,FBRL,FIB,FIB1,FLRN,Histone-glutamine methyltransferase,Nop1p,RNA U3 small nucleolar interacting protein 1,RNU3IP1,rRNA 2' O methyltransferase fibrillarin,rRNA 2'-O-methyltransferase fibrillarin

Background: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

Poids moléculaire:

Observed_MW: 36kDa

Calculated_MW: 33kDa

ID gène: 2091

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process