ETV1 anticorps
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- Antigène Voir toutes ETV1 Anticorps
- ETV1 (Ets Variant 1 (ETV1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ETV1 est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human ETV1 (NP_004947.2).
- Isotype
- IgG
- Top Product
- Discover our top product ETV1 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- ETV1 (Ets Variant 1 (ETV1))
- Autre désignation
- ETV1 (ETV1 Produits)
- Synonymes
- anticorps er81, anticorps XER81, anticorps MGC75591, anticorps ER81, anticorps Etsrp81, anticorps ETS variant 1, anticorps ets variant 1, anticorps ETS variant 1 S homeolog, anticorps etv1, anticorps ETV1, anticorps Etv1, anticorps etv1.S
- Sujet
- This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Poids moléculaire
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Calculated_MW: 43kDa/48kDa/50kDa/52kDa/53kDa/55kDa
- ID gène
- 2115
- UniProt
- P50549
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