GRIA4 anticorps (AA 296-325)

N° du produit ABIN656865

Détail du produit anti-GRIA4 anticorps

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Épitope: AA 296-325

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Pr, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GRIA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human GRIA4.

Clone: RB30232

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: GRIA4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-GRIA4 (ABIN656865)

Muntané, Horvath, Hof, Ely, Hopkins, Raghanti, Lewandowski, Wray, Sherwood: "Analysis of synaptic gene expression in the neocortex of primates reveals evolutionary changes in glutamatergic neurotransmission." dans: Cerebral cortex (New York, N.Y. : 1991), Vol. 25, Issue 6, pp. 1596-607, (2015) (PubMed).

Détails sur GRIA4

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Autre désignation: GRIA4 (GRIA4 Produits)

Synonymes: anticorps GLUR4, anticorps GLUR4C, anticorps GLURD, anticorps GluA4, anticorps GluR4, anticorps GluR4d, anticorps GLUR4/D, anticorps glur4, anticorps GluR-D, anticorps Glur-4, anticorps Glur4, anticorps Gluralpha4, anticorps spkw1, anticorps DKFZp459P0616, anticorps glur4a, anticorps gria4, anticorps iGluR4, anticorps ZfGluR4b, anticorps fj46g06, anticorps glur4b, anticorps wu:fj46g06, anticorps glutamate ionotropic receptor AMPA type subunit 4, anticorps glutamate receptor, ionotropic, AMPA 4, anticorps glutamate receptor, ionotropic, AMPA4 (alpha 4), anticorps glutamate receptor, ionotropic, AMPA 4a, anticorps glutamate receptor, ionotropic, AMPA 4b, anticorps GRIA4, anticorps gria4, anticorps Gria4, anticorps gria4a, anticorps gria4b

Sujet: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq].

Poids moléculaire: 100871

ID gène: 2893

NCBI Accession: NP_000820, NP_001070711, NP_001070712, NP_001106283

UniProt: P48058

Pathways: Signalisation PI3K-Akt