LRWD1 anticorps

N° du produit ABIN6568759

Détail du produit anti-LRWD1 anticorps

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRWD1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic peptide of human Lrwd1

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LRWD1

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Autre désignation: Lrwd1 (LRWD1 Produits)

Sujet:

Synonyms: 1200011O22Rik,AU042569,AW548074,DKFZp434K1815,Leucine rich repeats and WD repeat domain containing 1,Leucine-rich repeat and WD repeat-containing protein 1,LRWD1,LRWD1,ORC-associated protein,ORCA,Origin recognition complex-associated protein

Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 65kDa

Calculated_MW: 70kDa

ID gène: 222229

UniProt: Q9UFC0

Pathways: Chromatin Binding