DUSP4 anticorps
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- Antigène Voir toutes DUSP4 Anticorps
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
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Reactivité
- Humain, Singe
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DUSP4 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human DUSP4
- Isotype
- IgG
- Top Product
- Discover our top product DUSP4 Anticorps primaire
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- Indications d'application
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
- Autre désignation
- MKP-2 (DUSP4 Produits)
- Synonymes
- anticorps zgc:55423, anticorps DUSP4, anticorps typ, anticorps hvh2, anticorps mkp2, anticorps mkp-2, anticorps MGC131045, anticorps HVH2, anticorps MKP-2, anticorps MKP2, anticorps TYP, anticorps 2700078F24Rik, anticorps AI844617, anticorps BB104621, anticorps E130306H24Rik, anticorps Mkp-2, anticorps Mkp2, anticorps dual specificity phosphatase 4, anticorps dual specificity phosphatase 4 S homeolog, anticorps dusp4, anticorps DUSP4, anticorps dusp4.S, anticorps Dusp4
- Sujet
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Synonyms: Dual specificity phosphatase 4,Dual specificity protein phosphatase 4,Dual specificity protein phosphatase hVH2,DUS4,DUSP 4,Dusp4,HVH 2,HVH2,MAP kinase phosphatase 2,Mitogen activated protein kinase phosphatase 2,Mitogen-activated protein kinase phosphatase 2,MKP 2,MKP-2,MKP2,Serine/threonine specific protein phosphatase,TYP,Typ1,VH 2,VH1 homologous phosphatase 2,VH2
Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
- Poids moléculaire
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Observed_MW: 43kDa
Calculated_MW: 32kDa/42kDa
- ID gène
- 1846
- UniProt
- Q13115
- Pathways
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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