CD8B anticorps

N° du produit ABIN5965404

Détail du produit anti-CD8B anticorps

Antigène: CD8B (CD8b Molecule (CD8B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD8B est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human CD8B

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CD8B

Antigène: CD8B (CD8b Molecule (CD8B))

Autre désignation: CD8B (CD8B Produits)

Synonymes: anticorps Cd8b, anticorps Ly-3, anticorps Ly-C, anticorps Lyt-3, anticorps CD8B1, anticorps LEU2, anticorps LY3, anticorps LYT3, anticorps P37, anticorps Cd8b1, anticorps CD8b molecule, anticorps CD8 antigen, beta chain 1, anticorps Cd8b, anticorps CD8B, anticorps Cd8b1

Sujet:

Synonyms: CD8b antigen,CD8 antigen beta polypeptide 1 (p37),CD8 antigen beta polypeptide 1,CD8 beta,CD8b,CD8b molecule,CD8B,CD8B1,Leu2,Ly3,LYT3,MGC119115,P37,T cell surface glycoprotein CD8 beta chain,T lymphocyte surface glycoprotein beta chain,T-cell surface glycoprotein CD8 beta chain

Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Poids moléculaire:

Observed_MW: 45kDa

Calculated_MW: 20kDa/22kDa/23kDa/24kDa/25kDa/27kDa

ID gène: 926

UniProt: P10966

Pathways: TCR Signaling