CTPS2 anticorps (C-Term)

N° du produit ABIN656954

Détail du produit anti-CTPS2 anticorps

Antigène: CTPS2 (CTP Synthase II (CTPS2))

Épitope: AA 450-479, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTPS2 est non-conjugé

Application: Western Blotting (WB)

Homologie: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human CTPS2.

Clone: RB32822

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: CTPS2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur CTPS2

Antigène: CTPS2 (CTP Synthase II (CTPS2))

Autre désignation: CTPS2 (CTPS2 Produits)

Synonymes: anticorps A830031M15Rik, anticorps AI326475, anticorps Ctpsh, anticorps CTP synthase 2 L homeolog, anticorps CTP synthase 2, anticorps cytidine 5'-triphosphate synthase 2, anticorps ctps2.L, anticorps CTPS2, anticorps ctps2, anticorps Ctps2

Sujet: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.

Poids moléculaire: 65678

ID gène: 56474

NCBI Accession: NP_001137474, NP_062831, NP_787055

UniProt: Q9NRF8

Pathways: Ribonucleoside Biosynthetic Process