KREMEN2 anticorps (AA 248-276)
Aperçu rapide pour KREMEN2 anticorps (AA 248-276) (ABIN656978)
Antigène
Voir toutes KREMEN2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 248-276
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- KREMEN2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Date de péremption
- 6 months
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- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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Autre désignation
- KREMEN2
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Sujet
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
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Poids moléculaire
- 48849
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ID gène
- 79412
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NCBI Accession
- NP_001240654, NP_001240655, NP_078783, NP_757384
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UniProt
- Q8NCW0
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Pathways
- Signalisation WNT
Antigène
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