KREMEN2 anticorps (AA 248-276)

N° du produit ABIN656978

Détail du produit anti-KREMEN2 anticorps

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Épitope: AA 248-276

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KREMEN2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.

Clone: RB32950

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: KREMEN2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur KREMEN2

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Autre désignation: KREMEN2 (KREMEN2 Produits)

Synonymes: anticorps krm2, anticorps KREMEN2, anticorps MGC147633, anticorps KRM2, anticorps 2900054E04Rik, anticorps Krm2, anticorps kringle containing transmembrane protein 2 S homeolog, anticorps kringle containing transmembrane protein 2, anticorps kremen2.S, anticorps KREMEN2, anticorps kremen2, anticorps Kremen2

Sujet: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Poids moléculaire: 48849

ID gène: 79412

NCBI Accession: NP_001240654, NP_001240655, NP_078783, NP_757384

UniProt: Q8NCW0

Pathways: Signalisation WNT