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GNAS anticorps (C-Term)

GNAS Reactivité: Humain WB, IF, FACS, IHC (p) Hôte: Lapin Polyclonal RB33001 unconjugated
N° du produit ABIN656989
  • Antigène Voir toutes GNAS Anticorps
    GNAS (GNAS Complex Locus (GNAS))
    Épitope
    • 16
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 287-315, C-Term
    Reactivité
    • 85
    • 29
    • 25
    • 10
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 80
    • 9
    • 1
    Lapin
    Clonalité
    • 82
    • 8
    Polyclonal
    Conjugué
    • 50
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GNAS est non-conjugé
    Application
    • 74
    • 42
    • 33
    • 17
    • 16
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat, B, Ha, Pig
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This GNAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human GNAS.
    Clone
    RB33001
    Isotype
    IgG
    Top Product
    Discover our top product GNAS Anticorps primaire
  • Indications d'application
    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    GNAS Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Date de péremption
    6 months
  • Antigène
    GNAS (GNAS Complex Locus (GNAS))
    Autre désignation
    GNAS (GNAS Produits)
    Synonymes
    anticorps AHO, anticorps C20orf45, anticorps GNAS1, anticorps GPSA, anticorps GSA, anticorps GSP, anticorps NESP, anticorps PHP1A, anticorps PHP1B, anticorps PHP1C, anticorps POH, anticorps GNAS, anticorps PORGSA1, anticorps G-alpha-S, anticorps 5530400H20Rik, anticorps A930027G11Rik, anticorps C130027O20Rik, anticorps Galphas, anticorps Gnas1, anticorps Gnasxl, anticorps Gsa, anticorps Nesp, anticorps Nespl, anticorps Oed-Sml, anticorps Oedsml, anticorps P1, anticorps P2, anticorps P3, anticorps G-alpha-s, anticorps gnas-a, anticorps Gnpas, anticorps Nesp55, anticorps gnal, anticorps Gnas, anticorps GNAS complex locus, anticorps guanine nucleotide-binding protein G(s) subunit alpha, anticorps GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, anticorps GNAS complex locus S homeolog, anticorps neuroendocrine secretory protein 55-like, anticorps GNAS, anticorps LOC694289, anticorps LOC469986, anticorps Gnas, anticorps gnas.S, anticorps gnas, anticorps LOC100346323, anticorps LOC100442753, anticorps LOC100732436
    Sujet
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.
    Poids moléculaire
    44250
    ID gène
    2778
    UniProt
    Q5FWY2
    Pathways
    Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
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