Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
M, B
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This HIST1H2BN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BN.
anticorps H2B/d, anticorps H2BFD, anticorps HIST1H2BM, anticorps HIST1H2BN, anticorps histone cluster 1 H2B family member n, anticorps histone cluster 1, H2bn, anticorps HIST1H2BN, anticorps Hist1h2bn, anticorps HIST1H2BB
Sujet
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.