PCDHA12 anticorps (N-Term)

N° du produit ABIN657063

Détail du produit anti-PCDHA12 anticorps

Antigène: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Épitope: AA 166-194, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHA12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PCDHA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the N-terminal region of human PCDHA12.

Clone: RB32533

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PCDHA12

Antigène: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Autre désignation: PCDHA12 (PCDHA12 Produits)

Synonymes: anticorps PCDH-ALPHA12, anticorps Pcdha11, anticorps rCNRv12, anticorps Cnr5, anticorps Crnr5, anticorps Pcdha13, anticorps CNRv12, anticorps PCDHA12, anticorps protocadherin alpha 12, anticorps protocadherin alpha-12, anticorps PCDHA12, anticorps Pcdha12, anticorps LOC102147933

Sujet: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Poids moléculaire: 101652

NCBI Accession: NP_061726, NP_114070

UniProt: Q9UN75