ARID1A anticorps
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- Antigène Voir toutes ARID1A Anticorps
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARID1A est non-conjugé
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Application
- Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide of mouse BAF250 (NP_001074288.1).
- Isotype
- IgG
- Top Product
- Discover our top product ARID1A Anticorps primaire
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- Indications d'application
- IF 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
- Autre désignation
- BAF250 (ARID1A Produits)
- Synonymes
- anticorps B120, anticorps BAF250, anticorps BAF250a, anticorps BM029, anticorps C1orf4, anticorps ELD, anticorps MRD14, anticorps OSA1, anticorps P270, anticorps SMARCF1, anticorps hELD, anticorps hOSA1, anticorps 1110030E03Rik, anticorps Osa1, anticorps Smarcf1, anticorps ARID1A, anticorps wu:fb79b07, anticorps wu:fb95g08, anticorps zgc:171438, anticorps AT-rich interaction domain 1A, anticorps AT rich interactive domain 1A (SWI-like), anticorps AT rich interactive domain 1Aa (SWI-like), anticorps ARID1A, anticorps Arid1a, anticorps arid1a, anticorps arid1aa
- Sujet
- This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
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Calculated_MW: 206kDa/218kDa/242kDa
- ID gène
- 93760
- UniProt
- A2BH40
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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