PRKAB1 anticorps
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- Antigène Voir toutes PRKAB1 Anticorps
- PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PRKAB1 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- A synthetic peptide of human PRKAB1
- Isotype
- IgG
- Top Product
- Discover our top product PRKAB1 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
- Autre désignation
- PRKAB1 (PRKAB1 Produits)
- Synonymes
- anticorps AMPK, anticorps HAMPKb, anticorps 1300015D22Rik, anticorps AU021155, anticorps E430008F22, anticorps MGC82489, anticorps prkab1, anticorps wu:fk93d05, anticorps wu:fw87e09, anticorps zgc:56652, anticorps zgc:76975, anticorps zgc:92228, anticorps protein kinase AMP-activated non-catalytic subunit beta 1, anticorps protein kinase, AMP-activated, beta 1 non-catalytic subunit, anticorps protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog, anticorps protein kinase, AMP-activated, beta 1 non-catalytic subunit, b, anticorps protein kinase, AMP-activated, beta 1 non-catalytic subunit, a, anticorps PRKAB1, anticorps Prkab1, anticorps prkab1.S, anticorps prkab1, anticorps prkab1b, anticorps prkab1a
- Sujet
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
- Poids moléculaire
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Observed_MW: 37kDa
Calculated_MW: 30kDa
- ID gène
- 5564
- UniProt
- Q9Y478
- Pathways
- AMPK Signaling, L'effet Warburg
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