NDST1 anticorps (C-Term)

N° du produit ABIN657148

Détail du produit anti-NDST1 anticorps

Antigène: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Épitope: AA 820-849, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDST1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NDST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 820-849 amino acids from the C-terminal region of human NDST1.

Clone: RB33030

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur NDST1

Antigène: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Autre désignation: NDST1 (NDST1 Produits)

Synonymes: anticorps HSST, anticorps NST1, anticorps 1200015G06Rik, anticorps Hsst, anticorps NDST-1, anticorps fj47c03, anticorps ndst1, anticorps wu:fj47c03, anticorps NDST1, anticorps N-deacetylase and N-sulfotransferase 1, anticorps N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, anticorps N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b, anticorps N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 S homeolog, anticorps NDST1, anticorps Ndst1, anticorps ndst1b, anticorps ndst1, anticorps ndst1.S

Sujet: NDST1 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.

Poids moléculaire: 100868

NCBI Accession: NP_001534

UniProt: P52848

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process