XPC anticorps
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- Antigène Voir toutes XPC Anticorps
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp XPC est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human XPC (NP_004619.3).
- Isotype
- IgG
- Top Product
- Discover our top product XPC Anticorps primaire
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- Indications d'application
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
- Autre désignation
- XPC (XPC Produits)
- Synonymes
- anticorps RAD4, anticorps XP3, anticorps XPCC, anticorps XPC complex subunit, DNA damage recognition and repair factor, anticorps xeroderma pigmentosum, complementation group C, anticorps XPC, anticorps Xpc
- Sujet
- This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
- Poids moléculaire
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Observed_MW: 130kDa
Calculated_MW: 15kDa/101kDa/105kDa
- ID gène
- 7508
- UniProt
- Q01831
- Pathways
- Signalisation p53, Réparation de l'ADN
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