This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.
GFRA4
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Wang, Guo, Wang, Liu, Zhang, Cui, Wu: "Downregulation of microRNA-483-5p Promotes Cell Proliferation and Invasion by Targeting GFRA4 in Hirschsprung's Disease." dans: DNA and cell biology, Vol. 36, Issue 11, pp. 930-937, (2017) (PubMed).
anticorps zgc:171814, anticorps AW060733, anticorps G630015H18Rik, anticorps GDNF family receptor alpha 4, anticorps GDNF family receptor alpha 4a, anticorps glial cell line derived neurotrophic factor family receptor alpha 4, anticorps GFRA4, anticorps gfra4a, anticorps Gfra4
Sujet
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.