BCCIP anticorps
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- Antigène Voir toutes BCCIP Anticorps
- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BCCIP est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human BCCIP (NP_510868.1).
- Isotype
- IgG
- Top Product
- Discover our top product BCCIP Anticorps primaire
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- Indications d'application
- IHC 1:100-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
- Autre désignation
- BCCIP (BCCIP Produits)
- Synonymes
- anticorps zgc:110272, anticorps mp:zf637-1-000774, anticorps BCCIP, anticorps DKFZp459K2416, anticorps MGC82792, anticorps tok-1, anticorps MGC89311, anticorps TOK-1, anticorps TOK1, anticorps 1110013J05Rik, anticorps BRCA2 and CDKN1A interacting protein, anticorps BRCA2 and CDKN1A interacting protein L homeolog, anticorps BCCIP, anticorps bccip, anticorps bccip.L, anticorps Bccip
- Sujet
- This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
- Poids moléculaire
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Observed_MW: 50kDa
Calculated_MW: 33kDa/35kDa/36kDa
- ID gène
- 56647
- UniProt
- Q9P287
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