Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
B, M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This CHMP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP2B.
anticorps ALS17, anticorps CHMP2.5, anticorps DMT1, anticorps VPS2-2, anticorps VPS2B, anticorps 1190006E07Rik, anticorps RGD1306781, anticorps chmp2b, anticorps chmp2bl, anticorps zgc:77025, anticorps si:ch211-224m9.5, anticorps CHMP2B, anticorps cg4618, anticorps chmp2.5, anticorps dmt1, anticorps vps2-2, anticorps vps2b, anticorps CHMP2b-B, anticorps chmp2b-a, anticorps chmp2b-b, anticorps charged multivesicular body protein 2B, anticorps charged multivesicular body protein 2Bb, anticorps charged multivesicular body protein 2Ba, anticorps charged multivesicular body protein 2B pseudogene, anticorps charged multivesicular body protein 2B S homeolog, anticorps charged multivesicular body protein 2B L homeolog, anticorps CHMP2B, anticorps Chmp2b, anticorps chmp2bb, anticorps chmp2ba, anticorps LOC747711, anticorps chmp2b.S, anticorps chmp2b.L
Sujet
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.