Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ERO1L anticorps (C-Term)

ERO1L Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB33290 unconjugated
N° du produit ABIN657228
  • Antigène Voir toutes ERO1L Anticorps
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    Épitope
    • 16
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 350-379, C-Term
    Reactivité
    • 43
    • 4
    • 4
    Humain
    Hôte
    • 37
    • 5
    • 1
    Lapin
    Clonalité
    • 40
    • 2
    Polyclonal
    Conjugué
    • 20
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ERO1L est non-conjugé
    Application
    • 43
    • 22
    • 19
    • 16
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This ERO1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-379 amino acids from the C-terminal region of human ERO1L.
    Clone
    RB33290
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ERO1L Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    Autre désignation
    ERO1L (ERO1L Produits)
    Synonymes
    anticorps ERO1-L, anticorps ero1-alpha, anticorps ero1lb, anticorps ERO1L, anticorps ero1l, anticorps ERO1-alpha, anticorps ERO1A, anticorps zgc:63959, anticorps endoplasmic reticulum oxidoreductase alpha L homeolog, anticorps endoplasmic reticulum oxidoreductase 1 alpha, anticorps endoplasmic reticulum oxidoreductase alpha, anticorps ERO1-like (S. cerevisiae), anticorps ero1a.L, anticorps ERO1A, anticorps ero1a, anticorps Ero1l, anticorps Ero1a
    Sujet
    Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress. Required for the folding of immunoglobulin proteins. Responsible for the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin.
    Poids moléculaire
    54393
    NCBI Accession
    NP_055399
    UniProt
    Q96HE7
    Pathways
    Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation
Vous êtes ici:
Support technique