PCDHGA3 anticorps (AA 284-311)

N° du produit ABIN657534

Détail du produit anti-PCDHGA3 anticorps

Antigène: PCDHGA3 (PCDHgA3) (Protocadherin gamma A3 (PCDHgA3))

Épitope: AA 284-311

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHGA3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PCDHGA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 amino acids from the Central region of human PCDHGA3.

Clone: RB33029

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PCDHGA3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-PCDHGA3 (ABIN657534)

Zhang, Takata, Cui, Miyata-Takata, Sato, Noujima-Harada, Yoshino: "Protocadherin γ A3 is expressed in follicular lymphoma irrespective of BCL2 status and is associated with tumor cell growth." dans: Molecular medicine reports, Vol. 14, Issue 5, pp. 4622-4628, (2017) (PubMed).

Détails sur PCDHGA3

Antigène: PCDHGA3 (PCDHgA3) (Protocadherin gamma A3 (PCDHgA3))

Autre désignation: PCDHGA3 (PCDHgA3 Produits)

Synonymes: anticorps PCDH-GAMMA-A3, anticorps protocadherin gamma subfamily A, 3, anticorps PCDHGA3, anticorps Pcdhga3

Sujet: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Poids moléculaire: 100971

ID gène: 56112

NCBI Accession: NP_061739, NP_114400

UniProt: Q9Y5H0