Metabotropic Glutamate Receptor 6 anticorps (AA 369-398)

N° du produit ABIN657657

Détail du produit anti-Metabotropic Glutamate Receptor 6 anticorps

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Épitope: AA 369-398

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 6 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GRM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the Central region of human GRM6.

Clone: RB33716

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: GRM6 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur Metabotropic Glutamate Receptor 6

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Autre désignation: GRM6 (GRM6 Produits)

Synonymes: anticorps mGluR6, anticorps CSNB1B, anticorps GPRC1F, anticorps MGLUR6, anticorps mGlu6, anticorps GRM6, anticorps BC021919, anticorps Gm3, anticorps Gprc1f, anticorps nerg1, anticorps nob2, anticorps nob3, anticorps nob4, anticorps si:dkey-52h10.3, anticorps cb496, anticorps grma, anticorps zK13A21.16, anticorps zgc:158329, anticorps glutamate metabotropic receptor 6, anticorps glutamate receptor, metabotropic 6, anticorps glutamate receptor, metabotropic 6a, anticorps glutamate receptor, metabotropic 6b, anticorps Grm6, anticorps GRM6, anticorps grm6a, anticorps grm6b

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Poids moléculaire: 95468

ID gène: 2916

NCBI Accession: NP_000834

UniProt: O15303