This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SILV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 412-440 amino acids from the Central region of human SILV.
SILV plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.