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MBD3 anticorps (N-Term)

MBD3 Reactivité: Humain WB Hôte: Lapin Polyclonal RB33769 unconjugated
N° du produit ABIN657677
  • Antigène Voir toutes MBD3 Anticorps
    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
    Épitope
    • 13
    • 9
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivité
    • 69
    • 29
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 58
    • 9
    • 2
    Lapin
    Clonalité
    • 55
    • 14
    Polyclonal
    Conjugué
    • 41
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp MBD3 est non-conjugé
    Application
    • 45
    • 29
    • 9
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This MBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MBD3.
    Clone
    RB33769
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MBD3 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    MBD3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Date de péremption
    6 months
  • Antigène
    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
    Autre désignation
    MBD3 (MBD3 Produits)
    Synonymes
    anticorps xmbd3, anticorps MGC69548, anticorps MBD3, anticorps DKFZp459N1635, anticorps AI181826, anticorps AU019209, anticorps methyl-CpG binding domain protein 3 S homeolog, anticorps methyl-CpG binding domain protein 3, anticorps mbd3.S, anticorps mbd3, anticorps MBD3, anticorps Mbd3
    Sujet
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71 % and 94 % identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex.
    Poids moléculaire
    32844
    ID gène
    53615
    NCBI Accession
    NP_001268382, NP_001268383
    UniProt
    O95983
    Pathways
    Chromatin Binding
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