MBD3 anticorps (N-Term)
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- Antigène Voir toutes MBD3 Anticorps
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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Épitope
- AA 1-30, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MBD3 est non-conjugé
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Application
- Western Blotting (WB)
- Homologie
- M
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This MBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MBD3.
- Clone
- RB33769
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MBD3 Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- MBD3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- Autre désignation
- MBD3 (MBD3 Produits)
- Synonymes
- anticorps xmbd3, anticorps MGC69548, anticorps MBD3, anticorps DKFZp459N1635, anticorps AI181826, anticorps AU019209, anticorps methyl-CpG binding domain protein 3 S homeolog, anticorps methyl-CpG binding domain protein 3, anticorps mbd3.S, anticorps mbd3, anticorps MBD3, anticorps Mbd3
- Sujet
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71 % and 94 % identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex.
- Poids moléculaire
- 32844
- ID gène
- 53615
- NCBI Accession
- NP_001268382, NP_001268383
- UniProt
- O95983
- Pathways
- Chromatin Binding
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