RANGAP1 anticorps (N-Term)

N° du produit ABIN657698

Détail du produit anti-RANGAP1 anticorps

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Épitope: AA 20-49, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANGAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RANGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1.

Clone: RB33892

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: RANGAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur RANGAP1

Antigène: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Autre désignation: RANGAP1 (RANGAP1 Produits)

Synonymes: anticorps Fug1, anticorps RANGAP, anticorps SD, anticorps ATRANGAP1, anticorps RAN GTPASE-ACTIVATING PROTEIN 1, anticorps RAN GTPase activating protein 1, anticorps RanGAP1, anticorps fug1, anticorps rangap1b, anticorps rna1p, anticorps C79654, anticorps mKIAA1835, anticorps rangap1, anticorps rangap1a, anticorps Protein rna1, anticorps CG9999, anticorps CT28175, anticorps Dmel\CG9999, anticorps RGP1_DROME, anticorps Ran, anticorps RanGAP, anticorps RanGap, anticorps RanGap1, anticorps Scl, anticorps Sd, anticorps Sd-RanGAP, anticorps Sd-RanGap, anticorps dRanGAP, anticorps ranGAP, anticorps ranGap, anticorps rangap, anticorps zgc:154097, anticorps Ran GTPase activating protein 1, anticorps RAN GTPase activating protein 1, anticorps ran GTPase activating protein 1, anticorps Ran GTPase activating protein 1 S homeolog, anticorps Ran GTPase activating protein 1 L homeolog, anticorps Ran GAP Rna1, anticorps Ran GTPase activating protein, anticorps RAN GTPase activating protein 1a, anticorps RANGAP1, anticorps TERG_02084, anticorps rangap1.S, anticorps Rangap1, anticorps rangap1.L, anticorps rna1, anticorps RanGAP, anticorps rangap1a

Sujet: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

Poids moléculaire: 63542

ID gène: 5905

NCBI Accession: NP_001265580, NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus